摘要 :
Phytochemical investigation of Arenga pinnata(Wurmb.) Merr.fruits led to the isolation of 5 new compounds,designated A.pinnata A-E(1-5),and 13 known compounds(6-18).All compounds were isolated from A.pinnata for the first time.The...
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Phytochemical investigation of Arenga pinnata(Wurmb.) Merr.fruits led to the isolation of 5 new compounds,designated A.pinnata A-E(1-5),and 13 known compounds(6-18).All compounds were isolated from A.pinnata for the first time.Their chemical structures were identified based on extensive spectroscopic methods,including HR-ESI-MS,ID and 2D-NMR.To the best of our knowledge,this is the first systematic scientific study on the chemical composition of the Arenga genus.
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摘要 :
Supplemental Digital Content is available in the text. Rodent models for cerebral infarction are useful for studying human focal ischemic cerebral infarction, by simulating etiological and pathophysiological mechanisms. However, d...
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Supplemental Digital Content is available in the text. Rodent models for cerebral infarction are useful for studying human focal ischemic cerebral infarction, by simulating etiological and pathophysiological mechanisms. However, differences in the selection of anesthetic drugs, surgical methods and other factors may affect the extent to which preclinical models reflect the human condition. This review summarizes these factors. We searched pertinent literature from the MEDLINE and Web of Science databases, and reviewed differences in rodent strain, anesthesia method, sex, surgical method, timing of surgery, and factors influencing postoperative evaluation. In particular, circadian rhythm was found to have a significant impact on the outcome of cerebral infarction in rodent models. This information will enable researchers to quickly and clearly select appropriate modeling methods, acquire reliable quantitative experimental results, and obtain basic data for fundamental mechanism research.
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